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Paschim Vihar, New Delhi care@kpcirc.org

Cellular therapy

Stem cell & bone marrow transplant

High-dose treatment followed by restoration of the blood-forming system.

Referral & opinion only

What it is

Transplant replaces the blood-forming stem cells destroyed by very high-dose treatment, either with your own cells collected beforehand (autologous) or with a donor's (allogeneic).

An allogeneic transplant brings a second effect: the donor immune system itself acts against residual disease. It also brings graft-versus-host disease, which is why donor matching and long-term follow-up matter so much.

When it is used

  • In defined blood cancers, at defined points in the disease course
  • Where fitness, organ function and disease status meet the transplanting centre's criteria
  • Where a suitable donor is identified, for allogeneic transplant
Illustration
High-dose treatment, then restoration of the blood-forming system. Timing is often the whole decision.

How the decision is made

  • Whether transplant referral is appropriate, and when, timing is often the whole decision.
  • Which centre, and what the practical and financial burden on the family will realistically be.
  • What the alternatives are if transplant is not possible or not chosen.
Where it happens

Entirely at a designated transplant centre, with prolonged inpatient admission. KPCIRC does not perform transplants.

Who does what

What we handle, and what happens elsewhere

KPCIRC handles

  • Transplant-referral opinion from the haemato-oncology clinic
  • Complete case assembly before referral
  • Board review
  • Cost, scheme and assistance mapping
  • Long-term survivorship follow-up after return, including late effects and vaccination

Performed and billed elsewhere

  • Donor search and matching
  • Stem cell collection
  • Conditioning treatment
  • The transplant admission
  • All inpatient care
Delivered only where the licence and the intensive-care backup exist.
Safety, read this part
  • Infection risk after transplant is prolonged and serious. Fever after a transplant is always an emergency, however well you otherwise feel.

Questions to ask your own doctor

Take these with you. They work whether or not you are treated here.

  • Why now rather than later, or later rather than now?
  • Autologous or allogeneic, and why?
  • How long in hospital, and how long away from work and home?
  • What is the realistic total cost, and what schemes apply?
  • What is the plan for the years afterwards?

Not sure this is the right option for you?

That is exactly what a second opinion is for. Bring what you have, we will tell you what is missing and what the alternatives actually are, in writing.